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The NORI protocol is a revolutionary next-generation approach for the treatment of a wide range of cancers at all stages. This approach is selective and nontoxic which is a major departure from conventional cytotoxic therapy.

At the core of the NORI protocol are two key components which act together in a powerful and synergistic manner. Central to the NORI protocol is to limit antioxidant capacity of of cancer cells. Cancer cells are at the edge of survival due to a much higher basal level of oxidative stress (ROS) compared to normal cells. Cancer cells are highly dependent on the two major cellular antioxidant systems, glutathione and thioredoxin. These antioxidant systems can be inhibited which leads to an overload of intracellular oxidative stress(elevated ROS) which triggers cell death.

A methionine and cysteine restricted diet greatly lowers glutathione synthesis because glutathione is composed of cysteine, glycine and glutamate. There are many other benefits to a methionine and cysteine restricted diet but the primary benefit is in limiting glutathione synthesis. A methionine and cysteine restricted diet is 100% plant-based and carefully designed to limit intake of methionine and cysteine. Restricting these two sulfur containing amino acids offers numerous health and lifespan extending benefits.

Several nutraceuticals can target the thioredoxin antioxidant system. Sodium selenite is an excellent agent for inhibition of the thioredoxin antioxidant system. Sodium selenite has been extensively studied as a nontoxic selective chemotherapeutic agent in human clinical studies.

By combining a methionine and cysteine restricted diet a dual knockout of glutathione and thioredoxin antioxidant systems can be achieved which is deadly to cancer cells while causing no harm to normal cells. This approach represents a highly targeted therapy for treating nearly every form and stage of cancer.